Electrocardiography (ECG) – Detailed Overview
Definition
Electrocardiography is a non-invasive diagnostic procedure that records the electrical activity of the heart over time using surface electrodes. The graphical representation obtained is called an electrocardiogram.
Historical Background
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Late 19th century – Augustus Waller first recorded the human ECG (1887).
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1903 – Willem Einthoven developed the string galvanometer and introduced the standard limb leads (Lead I, II, III), earning the Nobel Prize (1924).
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Since then, ECG has evolved with 12-lead systems, portable Holter monitors, and computer-assisted interpretations.
Physiological Basis
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The heart’s rhythmic contraction is controlled by electrical impulses generated and conducted through:
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SA node → Atria → AV node → Bundle of His → Purkinje fibers → Ventricular muscle.
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Depolarization and repolarization of myocardial cells create electrical potentials detected by electrodes.
ECG Leads
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Standard Limb Leads – I, II, III (Einthoven's triangle).
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Augmented Limb Leads – aVR, aVL, aVF.
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Precordial Leads – V1 to V6.
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Together, these form the 12-lead ECG.
ECG Paper & Calibration
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Paper speed: 25 mm/sec.
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Vertical axis: 10 mm = 1 mV.
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Small square: 0.04 sec horizontally, 0.1 mV vertically.
Waves, Intervals, and Segments
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P wave – Atrial depolarization.
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PR interval – 0.12–0.20 sec; time for impulse from SA node to ventricles.
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QRS complex – Ventricular depolarization (normal <0.12 sec).
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T wave – Ventricular repolarization.
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ST segment – Time between depolarization and repolarization; isoelectric normally.
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QT interval – Ventricular depolarization + repolarization.
Normal ECG Values
| Parameter | Normal Range |
|---|---|
| Heart rate | 60–100 bpm |
| PR interval | 0.12–0.20 s |
| QRS duration | <0.12 s |
| QT interval | 0.35–0.44 s |
Clinical Uses
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Diagnosis of cardiac arrhythmias – e.g., atrial fibrillation, ventricular tachycardia.
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Detection of myocardial ischemia and infarction – ST elevation, T wave inversion, Q waves.
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Conduction defects – heart blocks, bundle branch blocks.
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Electrolyte imbalance – hyperkalemia (tall T waves), hypokalemia (U waves).
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Monitoring effects of drugs – e.g., digoxin, antiarrhythmics.
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Assessment of pacemaker function.
Advantages
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Non-invasive, inexpensive, and quick.
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Widely available and can be repeated frequently.
Limitations
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Provides only electrical information, not mechanical function.
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May miss intermittent or transient arrhythmias (need Holter monitoring).
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Requires correct electrode placement and patient cooperation.
Recent Advances
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Computerized ECG interpretation.
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Wearable continuous ECG devices.
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Tele-ECG for remote diagnosis.

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